Wednesday 10 October 2012

Nobel prize for Medicine 2012

My dear friend,
As we talk about Wallace( in my blog) and the pure heart in contibuting to the welfair of human kind( and living things) we have heard alot about recent work on stem cell.
Some friends have trouble with knee degeneration and will sure get' a younger knee' in the future with the fast developement of stem cell treament.Like to touch on the yearly event of Nobel prize and the work conributed.
The Nobel Prizes in science will be announced — one prize per day — between now and Wednesday. Today, the winners of the prize for physiology or medicine were announced. John Gurdon and Shinya Yamanaka will share the award for work related to cloning and our ability to manipulate the functioning of stem cells.
What's interesting here is that the research these two men are winning the Nobel for happened nearly a generation apart. Gurdon's work was crucial to the development of cloning. You'll recall that some embryonic stem cells can grow up to be anything, any part of animal's living tissue. Differentiated stem cells, in contrast, are destined for a specific job — for instance, they could grow into skin cells, or nerve cells, but not both. In 1952, other scientists had concluded that you could take genetic material from a very early frog embryo, inject it into the egg cell of another frog, and get that to grow into a living animal — a clone. But those researchers thought this process would only work up to a point. They didn't think you could clone an adult, or even an older fetus. Gurdon proved them wrong. In a series of experiments published between 1958, 1962, 1966, he worked with older and older donor cells, and produced more developed clones — eventually growing fully adult, fertile frogs from cells taken from the intestines of tadpoles.
Yamanaka, meanwhile, did his research in the early part of the 21st century, developing the methods that allow us to trick grown-up, set-in-their-ways cells into behaving more like embryonic stem cells. Yamanaka's work is linked to Gurdon's because it explains why Gurdon (and researchers after him) were able to successfully clone adult animals from cells that had fully differentiated.
The research history here is a little hard to follow, especially with Gurdon's work. The description of his findings I have here is what I've been able to piece together from several different sources, citing several different dates and specific achievements. To help cut through some of the confusion, here's a couple of links where you can get a good, reasonably detailed idea of what this research is, and why it matters:
This article on the history of cloning from the Proceedings of the National Academy of Sciences is easily readable and interesting, especially if your awareness of this topic begins with Dolly the Sheep. • In 2009, Gurdon and Yamanaka won the Albert Lasker Basic Medical Research Award. That organization has
a good explanation of how both men did their experiments and how their work ties together.

Aurora light

Solar Storm is strong and Aurora Polaris
seen at latitude north 35 degrees. during the extremely powerful solar storm recorded, north light , Aurora polaris was seen around equator. South light, Aurora Australasia is a smaller events.
Wishing you good luck in viewing Aurora.
Try youtube aurora goodle search.
quoted.
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Radiation hazards to humans (especially during day time)Intense solar flares release very-high-energy particles that can cause radiation poisoning to humans (and mammals in general) in the same way as low-energy radiation from nuclear blasts.Earth's
atmosphere and magnetosphere allow adequate protection at ground level, but astronauts in space are subject to potentially lethal doses of radiation. The penetration of high-energy particles into living cells can cause chromosome damage, cancer, and a host of other health problems. Large doses can be fatal immediately.Solar
protons with energies greater than 30 MeV are particularly hazardous. In October 1989, the Sun produced enough energetic particles that, if an astronaut were to have been standing on the Moon at the time, wearing only a space suit and caught out in the brunt of the storm, he would probably have died; the expected dose would be about 7000 rem[citation needed]. Note that astronauts who had time to gain safety in a shelter beneath moon soil would have absorbed only slight amounts of radiation.The cosmonauts on the
Mir station were subjected to daily doses of about twice the yearly dose on the ground, and during the solar storm at the end of 1989 they absorbed their full-year radiation dose limit in just a few hours.[citation needed]
Solar proton events can also produce elevated radiation aboard aircraft flying at high altitudes.

Saturday 6 October 2012

Sarawak,golden land,chapter ( )

Where is Sarawak ? Why Sarawak is very special ?
Sarawak is situated at the north west region of Borneo island. Alfred Russel Wallace published
'The Law of Sarawak' in 1885.
Who is Alfred R Wallace and what 'law' is this.
He was the codiscoverer of Natural selection and had the great contribution to mankind with Charles Darwin.
Alfred Wallace spent 18 months in Sarawak and it is in sarawak he wrote 'The Law of Sarawak'
which formed the foundation for the understanding of modern evolution, Biological science leading to genetic study
and modern medicine link with impact of research for advance total heatlh.
His work lead to research of Earth science with understanding of diversity of all living things.
He is a friend of living things.
Sarawak, therefore is the source of friends of living things.
Sarawak is the birth place of the pioneering theory of Alfred Wallace's Evolution Research.
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Why Sarawak became the place picked by Alfred Wallace for his heroic research of evolution ?
It linked with the special Glacial age or ice-age period that created Sundaland which included Borneo direct land link
with Asia continent. Imagine you were in Sarawak ten thousand years ago, the sea level is 390 feet lower than preset day sea level due to extensive ice formation over the earth. One could actually travel from Sarawak to Europe by land without any sea
such as present sea between Singapore and Sarawak.
What happen to the living things of Sarawak ?
Alfred Wallace picked the right spot with the help of Rajah James Brooke. Wallace firmly established his foundation of his theory of evolution in sarawak since the living things in Sarawak had the long period of time gone through natural selection and in contrast, compared to the living things of Australia, Alfred Wallace drew the conclusion.
The 'Wallace line' was declared and his research work was correct. The knowledge of his discovery is a proven tool
to future study and research.
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Sarawak got the advantage of ancient rain forest and thus the diversity of living things.
Imagine the Glacial age or ice-age with sea water surface temperature around freezing point. At that time eastern part
of Sarawak was covered with tropical rain forest due to the warmer sea over the east and south of Borneo.
Imagine snow cap peak of mountain Kinabalu at present Sabah state of Malaysia. It is a beautiful sight to compare the two adjacent region.
Sarawak became the centre of Alfred Wallace evolution research.
Base on the collection of living species of Sarawak , alfred Wallace observed and applied his knowledge of analysis and
found the conclusion of natural selection. At that time, more than 150 years ago, very little study had been done for the deep
sea trench east of Borneo, which actually seperated Borneo from Australasia. Can we say Alfred Wallace
was lucky to meet Sir James Brooke and eventually followed him to Sarawak and Sarawak is the place near to the deep deep sea trench east of Borneo. the trench caused the different type of diversity of livings of both side of the deep sea trench that enable Alfred Wallace to compare and eventually drew the right conclusion.
Evolution Theory
Lucky ? actually Luck only applicable to those who are well prepared for it
 
( written by Dr. Chong Mui Chun, James)